HORDB

ID: hor002827
Uniprot ID: Q8T0Y7
Protein name: CP2-derived peptide 4
Gene name: CP2PP
Organism: Aplysia californica (California sea hare)
Family: NA
Source: animal
Expression: Neurons.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: FSQAQGKVDMPLPRQRTSSRSSERWAPKS
Length: 29(69-97)
Propeptide: MDSRICTSFARLMASALCVSTLLVTAMPFDLRRGSSDTDLDLQGHVDLGLDDLDKLRLIFPPGLIEEAFSQAQGKVDMPLPRQRTSSRSSERWAPKSKRFDFGFAGLDTYDAIHRALEQPARGTSNSGSGYNMLMKMQRHG
Signal peptide: MDSRICTSFARLMASALCVSTLLVTA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002827_AF2.pdb

hor002827_ESM.pdb

Mass:	381829	Formula:	C141H229N47O44S
Absent amino acids:	CHINY	Common amino acids:	S
pI:	12.08	Basic residues:	6
Polar residues:	8	Hydrophobic residues:	6
Hydrophobicity:	-133.1	Boman Index:	-10472
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	30.34
Instability Index:	9402.07	Extinction Coefficient cystines:	5500
Absorbance 280nm:	196.43

PubMed ID: 11786187
Title: Cloning, Expression and Processing of the CP2 Neuropeptide Precursor of Aplysia